Biological and physical approaches on the role of piplartine (piperlongumine) in cancer

Abstract Chronic inflammation provides a favorable microenvironment for tumorigenesis, which opens opportunities for targeting cancer development and progression. Piplartine (PL) is a biologically active alkaloid from long peppers that exhibits anti-inflammatory and antitumor activity. In the presen...

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Bibliographic Details
Main Authors: Tiago Henrique, Caroline de F. Zanon, Ana P. Girol, Ana Carolina Buzzo Stefanini, Nayara S. de A. Contessoto, Nelson J. F. da Silveira, Daniel P. Bezerra, Edilberto R. Silveira, José M. Barbosa-Filho, Marinonio L. Cornélio, Sonia M. Oliani, Eloiza H. Tajara
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78220-6