A deep learning image-based intrinsic molecular subtype classifier of breast tumors reveals tumor heterogeneity that may affect survival

Abstract Background Breast cancer intrinsic molecular subtype (IMS) as classified by the expression-based PAM50 assay is considered a strong prognostic feature, even when controlled for by standard clinicopathological features such as age, grade, and nodal status, yet the molecular testing required...

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Bibliographic Details
Main Authors: Mustafa I. Jaber, Bing Song, Clive Taylor, Charles J. Vaske, Stephen C. Benz, Shahrooz Rabizadeh, Patrick Soon-Shiong, Christopher W. Szeto
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-020-1248-3