ERVK Polyprotein Processing and Reverse Transcriptase Expression in Human Cell Line Models of Neurological Disease

ERVK Polyprotein Processing and Reverse Transcriptase Expression in Human Cell Line Models of Neurological Disease

Enhanced expression of the reverse transcriptase (RT) protein encoded by human endogenous retrovirus-K (ERVK) is a promising biomarker for several inflammatory and neurological diseases. However, unlike RT enzymes encoded by exogenous retroviruses, little work has been done to identify ERVK RT isofo...

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Bibliographic Details
Main Authors: Mamneet Manghera, Jennifer Ferguson, Renée Douville
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Viruses
Subjects:
endogenous retrovirus
reverse transcriptase
astrocyte
neuron
neurological disease
inflammation
IFNγ
Online Access:http://www.mdpi.com/1999-4915/7/1/320

Internet

http://www.mdpi.com/1999-4915/7/1/320

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