Molecular pathway analysis towards understanding tissue vulnerability in spinocerebellar ataxia type 1

The neurodegenerative disorder spinocerebellar ataxia type 1 (SCA1) affects the cerebellum and inferior olive, though previous research has focused primarily on the cerebellum. As a result, it is unknown what molecular alterations are present in the inferior olive, and whether these changes are foun...

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Bibliographic Details
Main Authors: Terri M Driessen, Paul J Lee, Janghoo Lim
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/39981