Pairwise maximum entropy models for studying large biological systems: when they can work and when they can't.
One of the most critical problems we face in the study of biological systems is building accurate statistical descriptions of them. This problem has been particularly challenging because biological systems typically contain large numbers of interacting elements, which precludes the use of standard b...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-05-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2674569?pdf=render |