Differential regulation of NF-κB activation and function by topoisomerase II inhibitors

<p>Abstract</p> <p>Background</p> <p>While many common chemotherapeutic drugs and other inducers of DNA-damage result in both NF-κB nuclear translocation and DNA-binding, we have previously observed that, depending on the precise stimulus, there is great diversity of th...

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Bibliographic Details
Main Authors: Perkins Neil D, O'Shea John M, Campbell Kirsteen J
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/101