African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania.

X-linked Glucose-6-phosphate dehydrogenase (G6PD) A- deficiency is prevalent in sub-Saharan Africa populations, and has been associated with protection from severe malaria. Whether females and/or males are protected by G6PD deficiency is uncertain, due in part to G6PD and malaria phenotypic complexi...

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Bibliographic Details
Main Authors: Alphaxard Manjurano, Nuno Sepulveda, Behzad Nadjm, George Mtove, Hannah Wangai, Caroline Maxwell, Raimos Olomi, Hugh Reyburn, Eleanor M Riley, Christopher J Drakeley, Taane G Clark, MalariaGEN Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4335500?pdf=render