Kinetics and Signal Activation Properties of Circulating Factor(s) From Healthy Volunteers Undergoing Remote Ischemic Pre-Conditioning

Kinetics and Signal Activation Properties of Circulating Factor(s) From Healthy Volunteers Undergoing Remote Ischemic Pre-Conditioning

Although remote ischemic pre-conditioning (RIPC) reduced infarct size in animal experiments and proof-of-concept clinical trials, recent phase III trials failed to confirm cardioprotection during cardiac surgery. Here, we characterized the kinetic properties of humoral factors that are released afte...

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Bibliographic Details
Main Authors: Heike A. Hildebrandt, MD, Vincent Kreienkamp, MS, Sabine Gent, PhD, Philipp Kahlert, MD, Gerd Heusch, MD, PhD, Petra Kleinbongard, PhD
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:JACC: Basic to Translational Science
Subjects:
cardioprotection
human
humoral factor
kinetics
remote ischemic pre-conditioning
signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X16000127

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http://www.sciencedirect.com/science/article/pii/S2452302X16000127

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