Chondroitin sulfate synthase-2 is necessary for chain extension of chondroitin sulfate but not critical for skeletal development.

Chondroitin sulfate (CS) is a linear polysaccharide consisting of repeating disaccharide units of N-acetyl-D-galactosamine and D-glucuronic acid residues, modified with sulfated residues at various positions. Based on its structural diversity in chain length and sulfation patterns, CS provides speci...

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Bibliographic Details
Main Authors: Hiroyasu Ogawa, Sonoko Hatano, Nobuo Sugiura, Naoko Nagai, Takashi Sato, Katsuji Shimizu, Koji Kimata, Hisashi Narimatsu, Hideto Watanabe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22952769/?tool=EBI