CodY Regulates Thiol Peroxidase Expression as Part of the Pneumococcal Defense Mechanism against H2O2 Stress

CodY Regulates Thiol Peroxidase Expression as Part of the Pneumococcal Defense Mechanism against H2O2 Stress

Streptococcus pneumoniae is a facultative anaerobic pathogen. Although it maintains fermentative metabolism, during aerobic growth pneumococci produce high levels of H2O2, which can have adverse effects on cell viability and DNA, and influence pneumococcal interaction with its host. The pneumococcus...

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Bibliographic Details
Main Authors: Barak Hajaj, Hasan Yesilkaya, Sulman Shafeeq, Xiangyun Zhi, Rachel Benisty, Shiran Tchalah, Oscar P. Kuipers, Nurith Porat
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Streptococcus pneumoniae
TpxD
CodY
global gene regulation
H2O2
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00210/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00210/full

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