Fluoxetine-induced alteration of murine gut microbial community structure: evidence for a microbial endocrinology-based mechanism of action responsible for fluoxetine-induced side effects

Background Depression and major depressive disorder affect 25% of the population. First line treatment utilizing selective serotonin reuptake inhibitors (SSRIs) have met with limited success due to well-recognized negative side effects which include weight gain or loss. This inability to control unw...

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Bibliographic Details
Main Authors: Mark Lyte, Karrie M. Daniels, Stephan Schmitz-Esser
Format: Article
Language:English
Published: PeerJ Inc. 2019-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/6199.pdf