Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex

Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex

Abstract Background Exposure of the developing brain to immune mediators, including antibodies, is postulated to increase risk for neurodevelopmental disorders and neurodegenerative disease. It has been suggested that immunoglobulin G-immune complexes (IgG-IC) activate Fc gamma receptors (FcγR) expr...

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Bibliographic Details
Main Authors: Marianna Stamou, Ana Cristina Grodzki, Marc van Oostrum, Bernd Wollscheid, Pamela J. Lein
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Neuroinflammation
Subjects:
Fc gamma receptor (FcγR)
Neurons
Astrocytes
Hippocampus
Cortex
IgG immune complex (IgG-IC)
Online Access:http://link.springer.com/article/10.1186/s12974-017-1050-z

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http://link.springer.com/article/10.1186/s12974-017-1050-z

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