Isochoric supercooled preservation and revival of human cardiac microtissues

Powell-Palm et al. demonstrate sub-zero centigrade preservation and revival of autonomously beating, 3D human induced pluripotent stem cell (hiPSC)-derived cardiac microtissues via isochoric supercooling, without the use of chemical cryoprotectants. Their study suggests that functional 3D engineered...

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Bibliographic Details
Main Authors: Matthew J. Powell-Palm, Verena Charwat, Berenice Charrez, Brian Siemons, Kevin E. Healy, Boris Rubinsky
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02650-9