The N-Terminus of the HIV-1 p6 Gag Protein Regulates Susceptibility to Degradation by IDE

As part of the Pr55<sup>Gag</sup> polyprotein, p6 fulfills an essential role in the late steps of the replication cycle. However, almost nothing is known about the functions of the mature HIV-1 p6 protein. Recently, we showed that p6 is a bona fide substrate of the insulin-degrading enzy...

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Bibliographic Details
Main Authors: Adrian Schmalen, Julia Karius-Fischer, Pia Rauch, Christian Setz, Klaus Korn, Petra Henklein, Torgils Fossen, Ulrich Schubert
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Viruses
Subjects:
p6
L1P
Online Access:https://www.mdpi.com/1999-4915/10/12/710