Graft Pre-conditioning by Peri-Operative Perfusion of Kidney Allografts With Rabbit Anti-human T-lymphocyte Globulin Results in Improved Kidney Graft Function in the Early Post-transplantation Period—a Prospective, Randomized Placebo-Controlled Trial

Graft Pre-conditioning by Peri-Operative Perfusion of Kidney Allografts With Rabbit Anti-human T-lymphocyte Globulin Results in Improved Kidney Graft Function in the Early Post-transplantation Period—a Prospective, Randomized Placebo-Controlled Trial

Introduction: Although prone to a higher degree of ischemia reperfusion injury (IRI), the use of extended criteria donor (ECD) organs has become reality in transplantation. We therefore postulated that peri-operative perfusion of renal transplants with anti-human T-lymphocyte globulin (ATLG) amelior...

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Main Authors: Paul V. Ritschl, Julia Günther, Lena Hofhansel, Anja A. Kühl, Arne Sattler, Stefanie Ernst, Frank Friedersdorff, Susanne Ebner, Sascha Weiss, Claudia Bösmüller, Annemarie Weissenbacher, Rupert Oberhuber, Benno Cardini, Robert Öllinger, Stefan Schneeberger, Matthias Biebl, Christian Denecke, Christian Margreiter, Thomas Resch, Felix Aigner, Manuel Maglione, Johann Pratschke, Katja Kotsch
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
organ preservation
ATLG
ischemia reperfusion injury
RCT
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01911/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01911/full

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