Streptavidin-Hosted Organocatalytic Aldol Addition

In this report, the streptavidin-biotin technology was applied to enable organocatalytic aldol addition. By attaching pyrrolidine to the valeric motif of biotin and introducing it to streptavidin (Sav), a protein-based organocatalytic system was created, and the aldol addition of acetone with <i&...

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Bibliographic Details
Main Authors: Nicolò Santi, Louis C. Morrill, Louis Y. P. Luk
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/10/2457