Metabolic analyses elucidate nontrivial gene targets for amplifying dihydroartemisinic acid production in yeast

Metabolic analyses elucidate nontrivial gene targets for amplifying dihydroartemisinic acid production in yeast

Synthetic biology enables metabolic engineering of industrial microbes to synthesize value-added molecules. In this, a major challenge is the efficient redirection of carbon to the desired metabolic pathways. Pinpointing strategies toward this goal requires an in-depth investigation of the metabolic...

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Bibliographic Details
Main Authors: Ashish eMisra, Matthew F. Conway, Joseph eJohnnie, Tabish M. Qureshi, Anne M. Derrick, Eddy C. Agbo, Ganesh eSriram
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Microbiology
Subjects:
Isotope Labeling
Flux balance analysis
yeast
Metabolic Flux Analysis
metabolic pathway
Artemisinin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00200/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00200/full

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