Microarray Analysis in a Cell Death Resistant Glioma Cell Line to Identify Signaling Pathways and Novel Genes Controlling Resistance and Malignancy

Glioblastoma multiforme (GBM) is a lethal type of cancer mainly resistant to radio- and chemotherapy. Since the tumor suppressor p53 functions as a transcription factor regulating the expression of genes involved in growth inhibition, DNA repair and apoptosis, we previously assessed whether specific...

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Bibliographic Details
Main Authors: Janina Seznec, Ulrike Naumann
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Cancers
Subjects:
p53
IPA
Online Access:http://www.mdpi.com/2072-6694/3/3/2827/