Effect of inhaled air pollution particulate matter in alveolar macrophages on local pro-inflammatory cytokine and peripheral interferon γ production in response to Mycobacterium tuberculosis

Background: Human alveolar macrophages are first-line cellular responders to inhaled particulate matter (PM) and microbial pathogens in the lungs. We examined whether PM exposure affects human bronchoalveolar and peripheral blood mononuclear cell responses to Mycobacterium tuberculosis. Methods: Bro...

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Bibliographic Details
Main Authors: Yolanda Gonzalez, Claudia Carranza, Marco Iñiguez, Martha Torres, Raul Quintana, Alvaro Osornio, Carol Gardner, Srijata Sarkar, Stephan Schwander
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X1830158X