Restrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression.

Sensory hair cells and supporting cells of the mammalian inner ear are quiescent cells, which do not regenerate. In contrast, non-mammalian supporting cells have the ability to re-enter the cell cycle and produce replacement hair cells. Earlier studies have demonstrated cyclin D1 expression in the d...

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Bibliographic Details
Main Authors: Heidi Loponen, Jukka Ylikoski, Jeffrey H Albrecht, Ulla Pirvola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206952?pdf=render