Development of new promising antimetabolite, DFP-11207 with self-controlled toxicity in rodents

Development of new promising antimetabolite, DFP-11207 with self-controlled toxicity in rodents

Masakazu Fukushima, Kenzo Iizuka, Cheng Jin, Chun Zhang, Mei Hong, Kiyoshi Eshima Division of Oncology Research and Development, Delta-Fly Pharma Inc., Kawauchi-cho, Tokushima, Japan Abstract: To reduce 5-fluorouracil (5-FU)-induced serious toxicities without loss of antitumor activity, we have de...

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Bibliographic Details
Main Authors: Fukushima M, Iizuka K, Jin C, Zhang C, Hong M, Eshima K
Format: Article
Language:English
Published: Dove Medical Press 2017-06-01
Series:Drug Design, Development and Therapy
Subjects:
DFP-11207
5-FU
citrazinic acid
5-chloro-2
4-dihydroxypyridine
antitumor activity
myelo-toxicity
Online Access:https://www.dovepress.com/development-of-new-promising-antimetabolite-dfp-11207-with-self-contro-peer-reviewed-article-DDDT

Internet

https://www.dovepress.com/development-of-new-promising-antimetabolite-dfp-11207-with-self-contro-peer-reviewed-article-DDDT

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