Prolonged mechanical stretch initiates intracellular calcium oscillations in human mesenchymal stem cells.

Mesenchymal stem cells (MSCs) are a promising candidate for cell-based therapy in regenerative medicine. These stem cells can interact with their mechanical microenvironment to control their functions. External mechanical cues can be perceived and transmitted into intracellular calcium dynamics to r...

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Bibliographic Details
Main Authors: Tae-Jin Kim, Jie Sun, Shaoying Lu, Ying-Xin Qi, Yingxiao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4203723?pdf=render