Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice

Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice

The naphthoquinone buparvaquone is currently the only drug used against theileriosis. Here, the effects of buparvaquone were investigated in vitro and in an experimental mouse model for Neospora caninum infection. In 4-day proliferation assays, buparvaquone efficiently inhibited N. caninum tachyzoit...

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Bibliographic Details
Main Authors: Joachim Müller, Adriana Aguado-Martinez, Vera Manser, Vreni Balmer, Pablo Winzer, Dominic Ritler, Isabel Hostettler, David Arranz-Solís, Luis Ortega-Mora, Andrew Hemphill
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Neospora caninum
Neosporosis
Buparvaquone
Electron microscopy
Cerebral infection
Real time PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320715000032

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http://www.sciencedirect.com/science/article/pii/S2211320715000032

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