Triggering of Suicidal Erythrocyte Death by Zosuquidar

Triggering of Suicidal Erythrocyte Death by Zosuquidar

Background: The P-glycoprotein inhibitor zosuquidar (LY335979) is clinically used to augment the effect of cytostatic drugs on suicidal tumor cell death or apoptosis. The present study explored whether the substance is cytotoxic to erythrocytes. Upon injury, erythrocytes may undergo suicidal cell de...

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Bibliographic Details
Main Authors: Marilena Briglia, Antonella Fazio, Caterina Faggio, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Calcium
Cell volume
Eryptosis
Phosphatidylserine
SB203580
Calphostin
Online Access:http://www.karger.com/Article/FullText/438589

Internet

http://www.karger.com/Article/FullText/438589

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