Select targeting of intracellular Toll-interleukin-1 receptor resistance domains for protection against influenza-induced disease
TLRs are a family of PRRs that respond to PAMPs or host-derived Danger-Associated Molecular Patterns (DAMPs) to initiate host inflammation and immune responses. TLR dimerization and recruitment of adapter molecules is critical for intracellular signaling and is mediated through intracellular Toll-In...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-01-01
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Series: | Innate Immunity |
Online Access: | https://doi.org/10.1177/1753425919846281 |