Biomimetic modification of synthetic hydrogels by incorporation of adhesive peptides and calcium phosphate nanoparticles: in vitro evaluation of cell behavior

Biomimetic modification of synthetic hydrogels by incorporation of adhesive peptides and calcium phosphate nanoparticles: in vitro evaluation of cell behavior

The ultimate goal of this work was to develop a biocompatible and biomimetic in situ crosslinkable hydrogel scaffold with an instructive capacity for bone regenerative treatment. To this end, synthetic hydrogels were functionalized with two key components of the extracellular matrix of native bone t...

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Bibliographic Details
Main Authors: M Bongio, JJJP van den Beucken, MR Nejadnik, SCG Leeuwenburgh, LA Kinard, K Kasper, AG Mikos, JA Jansen
Format: Article
Language:English
Published: AO Research Institute Davos 2011-12-01
Series:European Cells & Materials
Subjects:
Synthetic polymers
biomimetic hydrogels
RGD peptide
calcium phosphate nanoparticles
cell-material interactions
in vitro mineralization
Online Access:http://www.ecmjournal.org/journal/papers/vol022/pdf/v022a27.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol022/pdf/v022a27.pdf

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