Isoquinoline Alkaloids Isolated from Corydalis yanhusuo and Their Binding Affinities at the Dopamine D1 Receptor

Isoquinoline Alkaloids Isolated from Corydalis yanhusuo and Their Binding Affinities at the Dopamine D1 Receptor

Bioactivity-guided fractionation of Corydalis yanhusuo has resulted in the isolation of eight known isoquinoline alkaloids - tetrahydropalmatine, isocorypalmine, stylopine, corydaline, columbamine, coptisin, 13-methylpalmatine, and dehydrocorybulbine. The tertiary alkaloids were further analyzed by...

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Bibliographic Details
Main Authors: David Y. W. Lee, Lee-Yuan Liu-Chen, Bryan L. Roth, Niels H. Jensen, Wei Xu, Zhong-Ze Ma
Format: Article
Language:English
Published: MDPI AG 2008-09-01
Series:Molecules
Subjects:
Corydalis yanhusuo
Isoquinoline alkaloids
d/l Ratio
Chiral HPLC
Dopamine receptor
Online Access:http://www.mdpi.com/1420-3049/13/9/2303/

Internet

http://www.mdpi.com/1420-3049/13/9/2303/

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