Myeloid-derived suppressor cells and nonresolving inflammatory cells in glioma microenvironment: molecular mechanisms and therapeutic strategies

Myeloid-derived suppressor cells and nonresolving inflammatory cells in glioma microenvironment: molecular mechanisms and therapeutic strategies

Myeloid-derived suppressor cells (MDSCs) are a subgroup of immunosuppressive heterogeneous cells derived from bone marrow (BM) stem cells. They not only strongly inhibit T cell-mediated antitumor immune response but also directly induce tumorigenesis and promote tumor growth and metastasis. Besides,...

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Bibliographic Details
Main Authors: Xiao-Yan Ji, Jia-Wei Ma, Jun Dong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Glioma
Subjects:
Glioma
molecular regulatory network
myeloid-derived suppressor cells
nonresolving inflammation
target therapy
tumor microenvironment
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2018;volume=1;issue=1;spage=2;epage=8;aulast=Ji

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http://www.jglioma.com/article.asp?issn=2589-6113;year=2018;volume=1;issue=1;spage=2;epage=8;aulast=Ji

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