Assessment of intestinal permeability of paclitaxel in the presence of NSAIDs and P-glycoprotein inhibitors

<p>Paclitaxel is a potent anticancer drug with a unique mechanism of action, which is now administered via IV infusion. Due to the presence of cremophor EL in its formulation it may show anaphylactic reactions. So that oral administration of paclitaxel for removal of these important side effec...

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Bibliographic Details
Main Authors: Zahra Sobhani, Hashem Montaseri, Soliman Mohammadi Samani, Fatemeh Ahmadi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2017-11-01
Series:Trends in Pharmaceutical Sciences
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/157