Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype
Airway remodelling is a critical feature of chronic bronchial diseases, characterised by aberrant repair of the epithelium and accumulation of fibroblasts, which contribute to extracellular matrix (ECM) deposition resulting in fixed bronchial obstruction. Recently, epithelial–mesenchymal transition...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
European Respiratory Society
2014-03-01
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Series: | European Respiratory Review |
Online Access: | http://err.ersjournals.com/content/23/131/118.full.pdf+html |