Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype

Airway remodelling is a critical feature of chronic bronchial diseases, characterised by aberrant repair of the epithelium and accumulation of fibroblasts, which contribute to extracellular matrix (ECM) deposition resulting in fixed bronchial obstruction. Recently, epithelial–mesenchymal transition...

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Bibliographic Details
Main Authors: Mallory Pain, Olga Bermudez, Philippe Lacoste, Pierre-Joseph Royer, Karine Botturi, Adrien Tissot, Sophie Brouard, Oliver Eickelberg, Antoine Magnan
Format: Article
Language:English
Published: European Respiratory Society 2014-03-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/23/131/118.full.pdf+html