Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers

Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers

Abstract Background Given the pathophysiological key role of the host response to an infection rather than the infection per se, an ideal therapeutic strategy would also target this response. This study was designed to demonstrate safety and feasibility of early therapeutic plasma exchange (TPE) in...

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Bibliographic Details
Main Authors: Hannah Knaup, Klaus Stahl, Bernhard M. W. Schmidt, Temitayo O. Idowu, Markus Busch, Olaf Wiesner, Tobias Welte, Hermann Haller, Jan T. Kielstein, Marius M. Hoeper, Sascha David
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Critical Care
Subjects:
Extracorporeal treatment
Plasmapheresis
Endothelium
Blood purification
Fresh frozen plasma
Online Access:http://link.springer.com/article/10.1186/s13054-018-2220-9

Internet

http://link.springer.com/article/10.1186/s13054-018-2220-9

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