Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species.

Besides being a marker of various somatic stem cells in mammals, prominin-1 (CD133) plays a role in maintaining the photoreceptor integrity since mutations in the PROM1 gene are linked with retinal degeneration. In spite of that, little information is available regarding its distribution in eyes of...

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Bibliographic Details
Main Authors: József Jászai, Christine A Fargeas, Sylvi Graupner, Elly M Tanaka, Michael Brand, Wieland B Huttner, Denis Corbeil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3047580?pdf=render