MTF1 Is Essential for the Expression of MT1B, MT1F, MT1G, and MT1H Induced by PHMG, but Not CMIT, in the Human Pulmonary Alveolar Epithelial Cells

MTF1 Is Essential for the Expression of MT1B, MT1F, MT1G, and MT1H Induced by PHMG, but Not CMIT, in the Human Pulmonary Alveolar Epithelial Cells

The inhalation of humidifier disinfectants (HDs) is linked to HD-associated lung injury (HDLI). Polyhexamethylene guanidine (PHMG) is significantly involved in HDLI, but the correlation between chloromethylisothiazolinone (CMIT) and HDLI remains ambiguous. Additionally, the differences in the molecu...

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Bibliographic Details
Main Authors: Sang-Hoon Jeong, Cherry Kim, Jaeyoung Kim, Yoon-Jeong Nam, Hong Lee, Ariunaa Togloom, Ja-Young Kang, Jin-Young Choi, Hyejin Lee, Myeong-Ok Song, Eun-Kee Park, Yong-Wook Baek, Ju-Han Lee, Ki-Yeol Lee
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Toxics
Subjects:
polyhexamethylene guanidine
chloromethylisothiazolinone
metallothionein 1
metal regulatory transcription factor 1
human pulmonary alveolar epithelial cells
Online Access:https://www.mdpi.com/2305-6304/9/9/203

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https://www.mdpi.com/2305-6304/9/9/203

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