Coenzyme Q10 Ameliorates Ultraviolet B Irradiation Induced Cell Death Through Inhibition of Mitochondrial Intrinsic Cell Death Pathway

Coenzyme Q10 Ameliorates Ultraviolet B Irradiation Induced Cell Death Through Inhibition of Mitochondrial Intrinsic Cell Death Pathway

Ultraviolet B (UVB) induces cell death by increasing free radical production, activating apoptotic cell death pathways and depolarizing mitochondrial membrane potential. Coenzyme Q10 (CoQ10), an essential cofactor in the mitochondrial electron transport chain, serves as a potent antioxidant in the m...

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Bibliographic Details
Main Authors: P. Andy Li, Santosh Kumari, Li Jing, Natalia Mendelev
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
caspase
cell death pathway
coenzyme Q10
mitochondria
ubiquinone 10
ultraviolet
Online Access:http://www.mdpi.com/1422-0067/12/11/8302/

Internet

http://www.mdpi.com/1422-0067/12/11/8302/

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