HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer

HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer

Background/Aims: HSP70/HSP90-organizing protein (HOP) is an adaptor protein that mediates heat shock protein 70 (HSP70) and HSP90 folding. HOP can be secreted by cancer cells and promote malignant cell growth in an autocrine manner. Here, we studied its role in gastric cancer (GC). Methods: HOP mRNA...

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Bibliographic Details
Main Authors: Ertao Zhai, Wei Liang, Yi Lin, Linlin Huang, Xin He, Shirong Cai, Jianhui Chen, Ning Zhang, Jiali Li, Qiuyang Zhang, Yulong He, Zhirong Zeng, Minhu Chen, Lixia Xu, Sui Peng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Gastric Cancer
Proliferation
Apoptosis
Hop
Autocrine
Online Access:https://www.karger.com/Article/FullText/490080

Internet

https://www.karger.com/Article/FullText/490080

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