Histamine 2 Receptor Agonism and Histamine 4 Receptor Antagonism Ameliorate Inflammation in a Model of Psoriasis

Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferative keratinocytes and immune cell infiltration into the skin, often accompanied by itch. Histamine, acting via histamine 1–4 receptors, is known to modulate immune responses in the skin and to induce itch. The aim of t...

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Bibliographic Details
Main Authors: Kristine Rossbach, Katharina Wahle, Gustav Bruer, Ralph Brehm, Marion Langeheine, Kristina Rode, Katrin Schaper-Gerhardt, Ralf Gutzmer, Thomas Werfel, Manfred Kietzmann, Wolfgang Bäumer
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2020-12-01
Series:Acta Dermato-Venereologica
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Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3674