The role of GLI1 for 5-Fu resistance in colorectal cancer

Abstract Colorectal cancer is a leading cause of cancer-related mortality worldwide, with Fluorouracil (5-FU)-based chemotherapy as the major treatment for advanced disease. Many patients with advanced colorectal cancer eventually succumb to the disease despite some patients responded initially to c...

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Bibliographic Details
Main Authors: Lining Zhang, Ruolan Song, Dongsheng Gu, Xiaoli Zhang, Beiqin Yu, Bingya Liu, Jingwu Xie
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Cell & Bioscience
Subjects:
EMT
Online Access:http://link.springer.com/article/10.1186/s13578-017-0145-7