A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

Abstract Background Chronic hepatitis B virus (HBV) infection leads to liver fibrosis, which is a major risk factor in hepatocellular carcinoma (HCC) and an independent risk factor of recurrence after HCC tumor resection. The HBV genome can be inserted into the human genome, and chronic inflammation...

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Bibliographic Details
Main Authors: Seungyeul Yoo, Wenhui Wang, Qin Wang, M Isabel Fiel, Eunjee Lee, Spiros P. Hiotis, Jun Zhu
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Medicine
Subjects:
HBV-HCC
HBV integration
Fusion transcript
Pathogenic SNPs
Tumor recurrence
Liver fibrosis
Online Access:http://link.springer.com/article/10.1186/s12916-017-0973-7

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http://link.springer.com/article/10.1186/s12916-017-0973-7

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