A flexible approach for highly multiplexed candidate gene targeted resequencing.

A flexible approach for highly multiplexed candidate gene targeted resequencing.

We have developed an integrated strategy for targeted resequencing and analysis of gene subsets from the human exome for variants. Our capture technology is geared towards resequencing gene subsets substantially larger than can be done efficiently with simplex or multiplex PCR but smaller in scale t...

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Bibliographic Details
Main Authors: Georges Natsoulis, John M Bell, Hua Xu, Jason D Buenrostro, Heather Ordonez, Susan Grimes, Daniel Newburger, Michael Jensen, Jacob M Zahn, Nancy Zhang, Hanlee P Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3127857?pdf=render

Internet

http://europepmc.org/articles/PMC3127857?pdf=render

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