Comparative Genomics and Disorder Prediction Identify Biologically Relevant SH3 Protein Interactions.

Protein interaction networks are an important part of the post-genomic effort to integrate a part-list view of the cell into system-level understanding. Using a set of 11 yeast genomes we show that combining comparative genomics and secondary structure information greatly increases consensus-based p...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-08-01
Series:PLoS Computational Biology
Online Access:http://dx.doi.org/10.1371/journal.pcbi.0010026