Host-based Th2 cell therapy for prolongation of cardiac allograft viability.

Donor T cell transfusion, which is a long-standing approach to prevent allograft rejection, operates indirectly by alteration of host T cell immunity. We therefore hypothesized that adoptive transfer of immune regulatory host Th2 cells would represent a novel intervention to enhance cardiac allograf...

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Bibliographic Details
Main Authors: Shoba Amarnath, Hao Chen, Jason E Foley, Carliann M Costanzo, Joel D Sennesh, Michael A Solomon, Daniel H Fowler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084712?pdf=render