Roles of Telomere Biology in Cell Senescence, Replicative and Chronological Ageing
Telomeres with G-rich repetitive DNA and particular proteins as special heterochromatin structures at the termini of eukaryotic chromosomes are tightly maintained to safeguard genetic integrity and functionality. Telomerase as a specialized reverse transcriptase uses its intrinsic RNA template to le...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-01-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2073-4409/8/1/54 |