Depleting Tumor Cells Expressing Immune Checkpoint Ligands—A New Approach to Combat Cancer

Antibodies against inhibitory immune checkpoint molecules (ICPMs), referred to as immune checkpoint inhibitors (ICIs), have gained a prominent place in cancer therapy. Several ICIs in clinical use have been engineered to be devoid of effector functions because of the fear that ICIs with preserved ef...

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Bibliographic Details
Main Authors: Fabrizio Marcucci, Cristiano Rumio
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
ADC
Online Access:https://www.mdpi.com/2073-4409/10/4/872