Generation of Feeder-Free Pig Induced Pluripotent Stem Cells without Pou5f1

The pig represents an ideal large-animal model, intermediate between rodents and humans, for the preclinical assessment of emerging cell therapies. As no validated pig embryonic stem (pES) cell lines have been derived so far, pig induced pluripotent stem cells (piPSCs) should offer an alternative so...

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Bibliographic Details
Main Authors: Nuria Montserrat, Lorena De Oñate, Elena Garreta, Federico Gonzãlez, Antonio Adamo, Cristina Eguizãbal, Sophia Häfner, Rita Vassena, Juan Carlos Izpisua Belmonte
Format: Article
Language:English
Published: SAGE Publishing 2012-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X601019