Modulation of GSK-3 as a therapeutic strategy on Tau pathologies
Glycogen synthase kinase 3 (GSK-3) is ubiquitously expressed and unusually active in resting, non-stimulated cells. In mammals, at least three proteins (, and generated from two different genes, gsk3 and gsk3 are widely expressed at both the RNA and protein levels although some tissues...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-10-01
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Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00024/full |