The Interaction of TRAF6 With Neuroplastin Promotes Spinogenesis During Early Neuronal Development

The Interaction of TRAF6 With Neuroplastin Promotes Spinogenesis During Early Neuronal Development

Correct brain wiring depends on reliable synapse formation. Nevertheless, signaling codes promoting synaptogenesis are not fully understood. Here, we report a spinogenic mechanism that operates during neuronal development and is based on the interaction of tumor necrosis factor receptor-associated f...

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Bibliographic Details
Main Authors: Sampath Kumar Vemula, Ayse Malci, Lennart Junge, Anne-Christin Lehmann, Ramya Rama, Johannes Hradsky, Ricardo A. Matute, André Weber, Matthias Prigge, Michael Naumann, Michael R. Kreutz, Constanze I. Seidenbecher, Eckart D. Gundelfinger, Rodrigo Herrera-Molina
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
dendritic protrusion
neuroplastin
E-I synapse balance
TRAF6
excitatory spinogenesis
synapse formation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.579513/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.579513/full

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