Serial examination of an inducible and reversible dilated cardiomyopathy in individual adult Drosophila.

Recent work has demonstrated that Drosophila can be used as a model of dilated cardiomyopathy, defined as an enlarged cardiac chamber at end-diastole when the heart is fully relaxed and having an impaired systolic function when the heart is fully contracted. Gene mutations that cause cardiac dysfunc...

Full description

Bibliographic Details
Main Authors: Il-Man Kim, Matthew J Wolf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2740824?pdf=render