Cerebral influx of Na+ and Cl− as the osmotherapy-mediated rebound response in rats

Cerebral influx of Na+ and Cl− as the osmotherapy-mediated rebound response in rats

Abstract Background Cerebral edema can cause life-threatening increase in intracranial pressure. Besides surgical craniectomy performed in severe cases, osmotherapy may be employed to lower the intracranial pressure by osmotic extraction of cerebral fluid upon intravenous infusion of mannitol or NaC...

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Bibliographic Details
Main Authors: Eva Kjer Oernbo, Kasper Lykke, Annette Buur Steffensen, Kathrin Töllner, Christina Kruuse, Martin Fredensborg Rath, Wolfgang Löscher, Nanna MacAulay
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Fluids and Barriers of the CNS
Subjects:
Osmotherapy
Rebound effect
Brain edema
Brain barriers
Ion-transporting mechanisms
Online Access:http://link.springer.com/article/10.1186/s12987-018-0111-8

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http://link.springer.com/article/10.1186/s12987-018-0111-8

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