Transient knockdown of tyrosine hydroxylase during development has persistent effects on behaviour in adult zebrafish (Danio rerio).

Abnormal dopamine (DA) signaling is often suggested as causative in schizophrenia. The other prominent hypothesis for this disorder, largely driven by epidemiological data, is that certain adverse events during the early stages of brain development increase an individual's risk of developing sc...

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Bibliographic Details
Main Authors: Isabel Formella, Ethan K Scott, Tom H J Burne, Lauren R Harms, Pei-Yun Liu, Karly M Turner, Xiaoying Cui, Darryl W Eyles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22879998/?tool=EBI