Limitation of number of strains and persistence of false positive loci in QTL mapping using recombinant inbred strains.

While the identification of causal genes of quantitative trait loci (QTL) remains a difficult problem in the post-genome era, the number of QTL continues to accumulate, mainly identified using the recombinant inbred (RI) strains. Over the last decade, hundreds of publications have reported nearly a...

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Bibliographic Details
Main Authors: Lishi Wang, Yan Jiao, Yanhong Cao, Gaifen Liu, Yongjun Wang, Weikuan Gu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4102522?pdf=render